STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crcB2Putative protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (124 aa)    
Predicted Functional Partners:
crcB
Putative protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
    
0.818
EFX40374.1
Chorismate mutase; COG: COG1605.
  
    0.802
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.556
fld
Flavodoxin; COG: COG0716.
     
 0.540
cadA
Cadmium-exporting ATPase; COG: COG2217.
   
  
 0.415
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.407
Your Current Organism:
Streptococcus peroris
NCBI taxonomy Id: 888746
Other names: S. peroris ATCC 700780, Streptococcus peroris ATCC 700780, Streptococcus peroris CCUG 39814, Streptococcus peroris CIP 105950, Streptococcus peroris GTC 848, Streptococcus peroris JCM 10158, Streptococcus peroris LMG 18719, Streptococcus peroris SK958, Streptococcus peroris str. ATCC 700780, Streptococcus peroris strain ATCC 700780
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