| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGJ41217.1 | ahrC | HMPREF9389_1214 | HMPREF9389_1221 | Hydrolase. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.517 |
| EGJ41217.1 | folD | HMPREF9389_1214 | HMPREF9389_1213 | Hydrolase. | Bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.888 |
| EGJ41217.1 | hlyA | HMPREF9389_1214 | HMPREF9389_1220 | Hydrolase. | Hemolysin A; COG: COG1189. | 0.518 |
| EGJ41217.1 | ispA | HMPREF9389_1214 | HMPREF9389_1219 | Hydrolase. | Geranyltranstransferase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | 0.542 |
| EGJ41217.1 | nnrD | HMPREF9389_1214 | HMPREF9389_1215 | Hydrolase. | Carbohydrate kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.668 |
| EGJ41217.1 | ptsG | HMPREF9389_1214 | HMPREF9389_2294 | Hydrolase. | PTS family glucose porter, IICBA component. | 0.638 |
| EGJ41217.1 | scrA | HMPREF9389_1214 | HMPREF9389_0992 | Hydrolase. | PTS family sucrose porter, EIIBC component ScrA; COG: COG1263. | 0.638 |
| EGJ41217.1 | treB | HMPREF9389_1214 | HMPREF9389_2242 | Hydrolase. | PTS family trehalose-specific porter, EIIBC component; COG: COG1263. | 0.638 |
| EGJ41217.1 | xseA | HMPREF9389_1214 | HMPREF9389_1217 | Hydrolase. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.520 |
| EGJ41217.1 | xseB | HMPREF9389_1214 | HMPREF9389_1218 | Hydrolase. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.518 |
| ahrC | EGJ41217.1 | HMPREF9389_1221 | HMPREF9389_1214 | Arginine repressor; Regulates arginine biosynthesis genes. | Hydrolase. | 0.517 |
| ahrC | folD | HMPREF9389_1221 | HMPREF9389_1213 | Arginine repressor; Regulates arginine biosynthesis genes. | Bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.696 |
| ahrC | hlyA | HMPREF9389_1221 | HMPREF9389_1220 | Arginine repressor; Regulates arginine biosynthesis genes. | Hemolysin A; COG: COG1189. | 0.900 |
| ahrC | ispA | HMPREF9389_1221 | HMPREF9389_1219 | Arginine repressor; Regulates arginine biosynthesis genes. | Geranyltranstransferase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | 0.891 |
| ahrC | nnrD | HMPREF9389_1221 | HMPREF9389_1215 | Arginine repressor; Regulates arginine biosynthesis genes. | Carbohydrate kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.881 |
| ahrC | xseA | HMPREF9389_1221 | HMPREF9389_1217 | Arginine repressor; Regulates arginine biosynthesis genes. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.888 |
| ahrC | xseB | HMPREF9389_1221 | HMPREF9389_1218 | Arginine repressor; Regulates arginine biosynthesis genes. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.888 |
| folD | EGJ41217.1 | HMPREF9389_1213 | HMPREF9389_1214 | Bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Hydrolase. | 0.888 |
| folD | ahrC | HMPREF9389_1213 | HMPREF9389_1221 | Bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.696 |
| folD | hlyA | HMPREF9389_1213 | HMPREF9389_1220 | Bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Hemolysin A; COG: COG1189. | 0.764 |
