APR75003.1 protein (Minicystis rosea) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

APR75003.1

TPR domain protein. (248 aa)

Predicted Functional Partners:

APR83368.1

0.703

APR75002.1

0.682

APR75308.1

0.664

APR78090.1

0.661

APR84603.1

0.650

APR79581.1

0.635

APR87172.1

0.626

APR86841.1

0.599

APR81565.1

0.574

APR77443.1

0.555

Your Current Organism:

Minicystis rosea

NCBI taxonomy Id: 888845
Other names: DSM 24000, M. rosea, Minicystis rosea Garcia et al. 2014, NCCB 100349, Sorangiineae bacterium SBNa008, strain SBNa008

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APR75002.1	APR75003.1	A7982_00348	A7982_00349	4Fe-4S ferredoxin, iron-sulfur binding protein.	TPR domain protein.	0.682
APR75003.1	APR75002.1	A7982_00349	A7982_00348	TPR domain protein.	4Fe-4S ferredoxin, iron-sulfur binding protein.	0.682
APR75003.1	APR75308.1	A7982_00349	A7982_00654	TPR domain protein.	TPR repeat protein.	0.664
APR75003.1	APR77443.1	A7982_00349	A7982_02790	TPR domain protein.	TPR domain protein.	0.555
APR75003.1	APR78090.1	A7982_00349	A7982_03437	TPR domain protein.	TPR Domain containing protein.	0.661
APR75003.1	APR79581.1	A7982_00349	A7982_04928	TPR domain protein.	Putrescine transport ATP-binding protein PotA.	0.635
APR75003.1	APR81565.1	A7982_00349	A7982_06914	TPR domain protein.	Type IV pilus biogenesis protein PilQ.	0.574
APR75003.1	APR83368.1	A7982_00349	A7982_08717	TPR domain protein.	TPR domain protein.	0.703
APR75003.1	APR84603.1	A7982_00349	A7982_09952	TPR domain protein.	TPR repeat protein.	0.650
APR75003.1	APR86841.1	A7982_00349	A7982_12190	TPR domain protein.	ABC transporter ATP-binding protein.	0.599
APR75003.1	APR87172.1	A7982_00349	A7982_12521	TPR domain protein.	Hypothetical protein.	0.626
APR75308.1	APR75003.1	A7982_00654	A7982_00349	TPR repeat protein.	TPR domain protein.	0.664
APR75308.1	APR77443.1	A7982_00654	A7982_02790	TPR repeat protein.	TPR domain protein.	0.607
APR75308.1	APR78090.1	A7982_00654	A7982_03437	TPR repeat protein.	TPR Domain containing protein.	0.471
APR75308.1	APR83368.1	A7982_00654	A7982_08717	TPR repeat protein.	TPR domain protein.	0.673
APR75308.1	APR84603.1	A7982_00654	A7982_09952	TPR repeat protein.	TPR repeat protein.	0.726
APR75308.1	APR87172.1	A7982_00654	A7982_12521	TPR repeat protein.	Hypothetical protein.	0.713
APR77443.1	APR75003.1	A7982_02790	A7982_00349	TPR domain protein.	TPR domain protein.	0.555
APR77443.1	APR75308.1	A7982_02790	A7982_00654	TPR domain protein.	TPR repeat protein.	0.607
APR77443.1	APR78090.1	A7982_02790	A7982_03437	TPR domain protein.	TPR Domain containing protein.	0.745

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

44

average node degree:

8

avg. local clustering coefficient:

0.878

expected number of edges:

18

PPI enrichment p-value:

1.55e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0071555

Cell wall organization

5 of 19

1.27

0.95

0.0038

GO:0007049

Cell cycle

4 of 16

1.25

0.93

0.0038

GO:0009252

Peptidoglycan biosynthetic process

5 of 21

1.23

0.92

0.0038

GO:0051301

Cell division

4 of 17

1.22

0.91

0.0038

GO:0008360

Regulation of cell shape

5 of 22

1.21

0.9

0.0038

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

6 of 25

1.23

1.19

0.00024

GO:0016881

Acid-amino acid ligase activity

4 of 10

1.45

1.11

0.0026

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:656

Mur ligase, central, and Mur ligase family, catalytic domain

5 of 7

1.7

2.1

1.08e-05

CL:653

Peptidoglycan biosynthesis, and Cytokinesis

6 of 12

1.55

2.01

3.79e-06

CL:372

Ribonucleoside monophosphate metabolic process, and glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

4 of 31

0.96

0.59

0.0190

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00471

D-Glutamine and D-glutamate metabolism

5 of 5

1.85

2.48

2.59e-06

map00550

Peptidoglycan biosynthesis

4 of 15

1.27

1.06

0.0014

map00220

Arginine biosynthesis

2 of 4

1.55

0.71

0.0369

map01100

Metabolic pathways

10 of 204

0.54

0.45

0.00045

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08245

Mur ligase middle domain

3 of 5

1.63

1.02

0.0075

PF02875

Mur ligase family, glutamate ligase domain

3 of 5

1.63

1.02

0.0075

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036615

Mur ligase, C-terminal domain superfamily

3 of 5

1.63

0.77

0.0282

IPR036565

Mur-like, catalytic domain superfamily

3 of 5

1.63

0.77

0.0282

IPR013221

Mur ligase, central

3 of 5

1.63

0.77

0.0282

IPR004101

Mur ligase, C-terminal

3 of 5

1.63

0.77

0.0282

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