APR78757.1 protein (Minicystis rosea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

APR78757.1

Hypothetical protein. (337 aa)

Predicted Functional Partners:

APR83212.1

0.790

APR82407.1

0.661

APR82406.1

0.620

APR86095.1

0.606

APR79308.1

0.595

APR78758.1

0.594

APR86803.1

0.552

APR85220.1

0.524

APR74938.1

0.499

APR78246.1

0.497

Your Current Organism:

Minicystis rosea

NCBI taxonomy Id: 888845
Other names: DSM 24000, M. rosea, Minicystis rosea Garcia et al. 2014, NCCB 100349, Sorangiineae bacterium SBNa008, strain SBNa008

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APR74938.1	APR78757.1	A7982_00284	A7982_04104	GMC oxidoreductase.	Hypothetical protein.	0.499
APR78246.1	APR78757.1	A7982_03593	A7982_04104	Choline dehydrogenase.	Hypothetical protein.	0.497
APR78757.1	APR74938.1	A7982_04104	A7982_00284	Hypothetical protein.	GMC oxidoreductase.	0.499
APR78757.1	APR78246.1	A7982_04104	A7982_03593	Hypothetical protein.	Choline dehydrogenase.	0.497
APR78757.1	APR78758.1	A7982_04104	A7982_04105	Hypothetical protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase.	0.594
APR78757.1	APR79308.1	A7982_04104	A7982_04655	Hypothetical protein.	Hypothetical protein.	0.595
APR78757.1	APR82406.1	A7982_04104	A7982_07755	Hypothetical protein.	Lipase precursor.	0.620
APR78757.1	APR82407.1	A7982_04104	A7982_07756	Hypothetical protein.	Lipase modulator protein.	0.661
APR78757.1	APR83212.1	A7982_04104	A7982_08561	Hypothetical protein.	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.	0.790
APR78757.1	APR85220.1	A7982_04104	A7982_10569	Hypothetical protein.	Hypothetical protein.	0.524
APR78757.1	APR86095.1	A7982_04104	A7982_11444	Hypothetical protein.	Polyhydroxyalkanoic acid synthase.	0.606
APR78757.1	APR86803.1	A7982_04104	A7982_12152	Hypothetical protein.	Hypothetical protein.	0.552
APR78758.1	APR78757.1	A7982_04105	A7982_04104	Delta-1-pyrroline-5-carboxylate dehydrogenase.	Hypothetical protein.	0.594
APR79308.1	APR78757.1	A7982_04655	A7982_04104	Hypothetical protein.	Hypothetical protein.	0.595
APR82406.1	APR78757.1	A7982_07755	A7982_04104	Lipase precursor.	Hypothetical protein.	0.620
APR82406.1	APR82407.1	A7982_07755	A7982_07756	Lipase precursor.	Lipase modulator protein.	0.970
APR82406.1	APR86803.1	A7982_07755	A7982_12152	Lipase precursor.	Hypothetical protein.	0.937
APR82407.1	APR78757.1	A7982_07756	A7982_04104	Lipase modulator protein.	Hypothetical protein.	0.661
APR82407.1	APR82406.1	A7982_07756	A7982_07755	Lipase modulator protein.	Lipase precursor.	0.970
APR82407.1	APR86803.1	A7982_07756	A7982_12152	Lipase modulator protein.	Hypothetical protein.	0.708

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

44

average node degree:

8

avg. local clustering coefficient:

0.878

expected number of edges:

18

PPI enrichment p-value:

1.55e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0071555

Cell wall organization

5 of 19

1.27

0.95

0.0038

GO:0007049

Cell cycle

4 of 16

1.25

0.93

0.0038

GO:0009252

Peptidoglycan biosynthetic process

5 of 21

1.23

0.92

0.0038

GO:0051301

Cell division

4 of 17

1.22

0.91

0.0038

GO:0008360

Regulation of cell shape

5 of 22

1.21

0.9

0.0038

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

6 of 25

1.23

1.19

0.00024

GO:0016881

Acid-amino acid ligase activity

4 of 10

1.45

1.11

0.0026

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:656

Mur ligase, central, and Mur ligase family, catalytic domain

5 of 7

1.7

2.1

1.08e-05

CL:653

Peptidoglycan biosynthesis, and Cytokinesis

6 of 12

1.55

2.01

3.79e-06

CL:372

Ribonucleoside monophosphate metabolic process, and glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

4 of 31

0.96

0.59

0.0190

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00471

D-Glutamine and D-glutamate metabolism

5 of 5

1.85

2.48

2.59e-06

map00550

Peptidoglycan biosynthesis

4 of 15

1.27

1.06

0.0014

map00220

Arginine biosynthesis

2 of 4

1.55

0.71

0.0369

map01100

Metabolic pathways

10 of 204

0.54

0.45

0.00045

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08245

Mur ligase middle domain

3 of 5

1.63

1.02

0.0075

PF02875

Mur ligase family, glutamate ligase domain

3 of 5

1.63

1.02

0.0075

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036615

Mur ligase, C-terminal domain superfamily

3 of 5

1.63

0.77

0.0282

IPR036565

Mur-like, catalytic domain superfamily

3 of 5

1.63

0.77

0.0282

IPR013221

Mur ligase, central

3 of 5

1.63

0.77

0.0282

IPR004101

Mur ligase, C-terminal

3 of 5

1.63

0.77

0.0282

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (10%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About