node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APR77143.1 | APR79375.1 | A7982_02490 | A7982_04722 | DNA polymerase III alpha subunit protein. | DNA polymerase III epsilon subunit protein. | 0.987 |
APR77143.1 | APR80325.1 | A7982_02490 | A7982_05672 | DNA polymerase III alpha subunit protein. | DNA polymerase III delta prime subunit protein. | 0.991 |
APR77143.1 | APR81260.1 | A7982_02490 | A7982_06607 | DNA polymerase III alpha subunit protein. | DNA polymerase III delta subunit protein. | 0.997 |
APR77143.1 | APR83297.1 | A7982_02490 | A7982_08646 | DNA polymerase III alpha subunit protein. | DNA polymerase III alpha subunit protein. | 0.987 |
APR77143.1 | APR83893.1 | A7982_02490 | A7982_09242 | DNA polymerase III alpha subunit protein. | DNA polymerase III beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | 0.998 |
APR77143.1 | APR86611.1 | A7982_02490 | A7982_11960 | DNA polymerase III alpha subunit protein. | DNA polymerase III subunits gamma and tau. | 0.992 |
APR77143.1 | dinB | A7982_02490 | A7982_06304 | DNA polymerase III alpha subunit protein. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.871 |
APR77143.1 | lexA | A7982_02490 | A7982_01455 | DNA polymerase III alpha subunit protein. | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.729 |
APR79375.1 | APR77143.1 | A7982_04722 | A7982_02490 | DNA polymerase III epsilon subunit protein. | DNA polymerase III alpha subunit protein. | 0.987 |
APR79375.1 | APR80325.1 | A7982_04722 | A7982_05672 | DNA polymerase III epsilon subunit protein. | DNA polymerase III delta prime subunit protein. | 0.985 |
APR79375.1 | APR81260.1 | A7982_04722 | A7982_06607 | DNA polymerase III epsilon subunit protein. | DNA polymerase III delta subunit protein. | 0.993 |
APR79375.1 | APR83297.1 | A7982_04722 | A7982_08646 | DNA polymerase III epsilon subunit protein. | DNA polymerase III alpha subunit protein. | 0.927 |
APR79375.1 | APR83893.1 | A7982_04722 | A7982_09242 | DNA polymerase III epsilon subunit protein. | DNA polymerase III beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | 0.998 |
APR79375.1 | APR86611.1 | A7982_04722 | A7982_11960 | DNA polymerase III epsilon subunit protein. | DNA polymerase III subunits gamma and tau. | 0.984 |
APR79375.1 | dinB | A7982_04722 | A7982_06304 | DNA polymerase III epsilon subunit protein. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.730 |
APR79375.1 | dnaE2 | A7982_04722 | A7982_12724 | DNA polymerase III epsilon subunit protein. | DNA polymerase III alpha subunit protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.883 |
APR79375.1 | lexA | A7982_04722 | A7982_01455 | DNA polymerase III epsilon subunit protein. | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.777 |
APR80325.1 | APR77143.1 | A7982_05672 | A7982_02490 | DNA polymerase III delta prime subunit protein. | DNA polymerase III alpha subunit protein. | 0.991 |
APR80325.1 | APR79375.1 | A7982_05672 | A7982_04722 | DNA polymerase III delta prime subunit protein. | DNA polymerase III epsilon subunit protein. | 0.985 |
APR80325.1 | APR81260.1 | A7982_05672 | A7982_06607 | DNA polymerase III delta prime subunit protein. | DNA polymerase III delta subunit protein. | 0.998 |