APR84505.1 protein (Minicystis rosea) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Score

APR84505.1

Mannose-1-phosphate guanylyltransferase (GDP). (364 aa)

Predicted Functional Partners:

APR83813.1

0.972

gmd

0.961

APR76353.1

0.939

APR81007.1

0.932

APR76195.1

0.732

APR85084.1

0.731

APR85430.1

0.643

APR84506.1

0.564

APR80480.1

0.501

APR76385.1

0.480

Your Current Organism:

Minicystis rosea

NCBI taxonomy Id: 888845
Other names: DSM 24000, M. rosea, Minicystis rosea Garcia et al. 2014, NCCB 100349, Sorangiineae bacterium SBNa008, strain SBNa008

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APR76195.1	APR76385.1	A7982_01542	A7982_01732	Undecaprenyl-phosphate galactosephosphotransferase.	Capsule polysaccharide export protein.	0.817
APR76195.1	APR80480.1	A7982_01542	A7982_05827	Undecaprenyl-phosphate galactosephosphotransferase.	Glucose-1-phosphate thymidylyltransferase.	0.518
APR76195.1	APR84505.1	A7982_01542	A7982_09854	Undecaprenyl-phosphate galactosephosphotransferase.	Mannose-1-phosphate guanylyltransferase (GDP).	0.732
APR76195.1	APR85430.1	A7982_01542	A7982_10779	Undecaprenyl-phosphate galactosephosphotransferase.	Capsular polysaccharide synthesis enzyme CpsD, exopolysaccharide synthesis.	0.956
APR76195.1	gmd	A7982_01542	A7982_07500	Undecaprenyl-phosphate galactosephosphotransferase.	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.	0.733
APR76353.1	APR80480.1	A7982_01700	A7982_05827	Nucleotidyl transferase.	Glucose-1-phosphate thymidylyltransferase.	0.767
APR76353.1	APR81007.1	A7982_01700	A7982_06354	Nucleotidyl transferase.	Phosphomannomutase.	0.939
APR76353.1	APR83813.1	A7982_01700	A7982_09162	Nucleotidyl transferase.	Phosphomannomutase.	0.951
APR76353.1	APR84505.1	A7982_01700	A7982_09854	Nucleotidyl transferase.	Mannose-1-phosphate guanylyltransferase (GDP).	0.939
APR76353.1	gmd	A7982_01700	A7982_07500	Nucleotidyl transferase.	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.	0.919
APR76385.1	APR76195.1	A7982_01732	A7982_01542	Capsule polysaccharide export protein.	Undecaprenyl-phosphate galactosephosphotransferase.	0.817
APR76385.1	APR84505.1	A7982_01732	A7982_09854	Capsule polysaccharide export protein.	Mannose-1-phosphate guanylyltransferase (GDP).	0.480
APR76385.1	APR85084.1	A7982_01732	A7982_10433	Capsule polysaccharide export protein.	Hypothetical protein.	0.741
APR76385.1	APR85430.1	A7982_01732	A7982_10779	Capsule polysaccharide export protein.	Capsular polysaccharide synthesis enzyme CpsD, exopolysaccharide synthesis.	0.989
APR76385.1	gmd	A7982_01732	A7982_07500	Capsule polysaccharide export protein.	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.	0.516
APR80480.1	APR76195.1	A7982_05827	A7982_01542	Glucose-1-phosphate thymidylyltransferase.	Undecaprenyl-phosphate galactosephosphotransferase.	0.518
APR80480.1	APR76353.1	A7982_05827	A7982_01700	Glucose-1-phosphate thymidylyltransferase.	Nucleotidyl transferase.	0.767
APR80480.1	APR83813.1	A7982_05827	A7982_09162	Glucose-1-phosphate thymidylyltransferase.	Phosphomannomutase.	0.936
APR80480.1	APR84505.1	A7982_05827	A7982_09854	Glucose-1-phosphate thymidylyltransferase.	Mannose-1-phosphate guanylyltransferase (GDP).	0.501
APR80480.1	APR85084.1	A7982_05827	A7982_10433	Glucose-1-phosphate thymidylyltransferase.	Hypothetical protein.	0.502

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Network Stats

number of nodes:

10

number of edges:

19

average node degree:

3.8

avg. local clustering coefficient:

0.628

expected number of edges:

15

PPI enrichment p-value:

0.202

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000160

Phosphorelay signal transduction system

8 of 85

1.43

2.12

9.28e-08

GO:0050794

Regulation of cellular process

10 of 232

1.09

1.37

9.28e-08

GO:1902531

Regulation of intracellular signal transduction

2 of 5

2.06

0.94

0.0170

GO:0019538

Protein metabolic process

8 of 297

0.89

0.84

7.70e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000155

Phosphorelay sensor kinase activity

7 of 44

1.66

2.64

6.88e-08

GO:0016772

Transferase activity, transferring phosphorus-containing groups

8 of 172

1.13

1.32

2.26e-06

GO:0140096

Catalytic activity, acting on a protein

8 of 192

1.08

1.22

4.09e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1813

Signal transduction histidine kinase-related protein, C-terminal

8 of 16

2.16

5.42

3.30e-13

CL:1816

Mixed, incl. Regulation of signaling, and PAS fold-4

7 of 11

2.26

5.23

5.66e-12

CL:1808

GGDEF domain, and Histidine kinase domain

9 of 60

1.64

3.39

5.70e-12

CL:1819

Regulation of signaling, and HPT domain superfamily

4 of 5

2.36

3.28

3.80e-07

CL:1802

Signaling, and GGDEF domain

10 of 105

1.44

2.68

5.70e-12

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0418

Kinase

7 of 90

1.35

1.76

1.43e-06

KW-0597

Phosphoprotein

6 of 75

1.36

1.62

1.14e-05

KW-0175

Coiled coil

8 of 232

1.0

1.05

1.14e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005467

Histidine kinase domain

8 of 42

1.74

3.35

4.41e-10

IPR003594

Histidine kinase/HSP90-like ATPase

8 of 45

1.71

3.26

4.41e-10

IPR036890

Histidine kinase/HSP90-like ATPase superfamily

8 of 48

1.68

3.19

4.41e-10

IPR004358

Signal transduction histidine kinase-related protein, C-terminal

7 of 38

1.72

3.02

7.34e-09

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

7 of 39

1.71

2.99

7.34e-09

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00387

Histidine kinase-like ATPases

8 of 44

1.72

3.49

5.14e-11

SM00388

His Kinase A (phosphoacceptor) domain

7 of 39

1.71

3.16

1.44e-09

SM00091

PAS domain

6 of 28

1.79

3.12

1.16e-08

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

5 of 19

1.88

2.93

1.56e-07

SM00448

cheY-homologous receiver domain

7 of 57

1.55

2.56

1.09e-08

(more ...)

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