STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APR84626.1DegP protease. (311 aa)    
Predicted Functional Partners:
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
 
  
 0.596
leuS
Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
    0.535
APR87147.1
Chemotaxis protein methyltransferase CheR.
  
  
 0.525
APR78272.1
Putative SigmaB asociated two-component system sensor protein.
  
  
 0.511
APR75389.1
Serine protease precursor MucD/AlgY associated with sigma factor RpoE.
  
     0.500
APR78289.1
PAS/PAC sensor hybrid histidine kinase precursor.
  
  
 0.499
APR74880.1
Chemotaxis protein methyltransferase CheR.
  
  
 0.497
APR83664.1
HtrA family serine protease.
  
     0.495
APR83481.1
Oxidoreductase, short chain dehydrogenase/reductase family protein.
    
 0.484
APR83770.1
Acetoacetyl-CoA reductase.
    
 0.484
Your Current Organism:
Minicystis rosea
NCBI taxonomy Id: 888845
Other names: DSM 24000, M. rosea, Minicystis rosea Garcia et al. 2014, NCCB 100349, Sorangiineae bacterium SBNa008, strain SBNa008
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.