STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFG36196.1PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. (174 aa)    
Predicted Functional Partners:
AFG38361.1
PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
  
  
  0.976
AFG36785.1
PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component.
 
  
 0.796
AFG36423.1
PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
  
     0.775
AFG36783.1
Phosphotransferase system HPr (HPr) family protein; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PTS HPr component phosphorylation site; PEP-utilising enzyme, N-terminal; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase System HPr (HPr) Family.
 
  
 0.678
AFG36198.1
Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein; TIGRFAM: phosphoribosylformylglycinamidine synthase I.
       0.571
AFG36784.1
1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
 
  
 0.568
purL
Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...]
       0.558
AFG36199.1
Hypothetical protein; PFAM: Uncharacterised ACR, COG1259; UvrB/uvrC motif.
       0.469
AFG37534.1
Phosphoenolpyruvate-protein phosphotransferase; PFAM: GAF domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
 
   
 0.457
AFG38023.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.441
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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