STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFG36241.1Anion transporter; PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter. (487 aa)    
Predicted Functional Partners:
AFG36239.1
PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit.
 
   
 0.841
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
  
 0.818
AFG36238.1
PFAM: Aldehyde dehydrogenase family.
  
  
 0.744
AFG36237.1
PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family.
       0.725
AFG36242.1
Putative permease; PFAM: Sulfite exporter TauE/SafE.
  
    0.700
AFG36235.1
Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain.
       0.681
AFG36236.1
Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
       0.681
AFG36244.1
PFAM: Glycosyl hydrolases family 31; Belongs to the glycosyl hydrolase 31 family.
     
 0.554
AFG36243.1
Hypothetical protein.
       0.528
AFG36245.1
Hypothetical protein.
       0.528
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.