STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (368 aa)    
Predicted Functional Partners:
AFG36479.1
PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase.
 
  
 0.995
AFG36480.1
PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
   
 0.975
AFG36477.1
PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: mevalonate kinase.
 
   
 0.958
AFG36482.1
3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal; TIGRFAM: 3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade.
 
  
 0.949
AFG37718.1
Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.931
AFG36478.1
PFAM: GHMP kinases N terminal domain.
 
   
 0.857
AFG36476.1
Lysophospholipase.
 
   
 0.811
AFG37663.1
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.807
AFG36351.1
FAD/FMN-dependent dehydrogenase; PFAM: D-arabinono-1,4-lactone oxidase; FAD binding domain.
  
 0.715
AFG36483.1
PFAM: Cyclic nucleotide-binding domain.
       0.634
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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