STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AFG36548.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (394 aa)    
Predicted Functional Partners:
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
       0.773
AFG36549.1
PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
       0.746
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
 
 0.573
truA
Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
 
 0.546
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
    0.506
AFG38317.1
3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; PFAM: FabA-like domain.
  
  
 0.494
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.471
AFG36787.1
Disulfide bond chaperone; PFAM: Hsp33 protein.
 
  
 0.470
mnmA
Putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase with PP-loop ATPase domain; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.428
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
  
 0.427
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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