STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFG36700.1RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (288 aa)    
Predicted Functional Partners:
dnaG
DNA primase, catalytic core; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
  
 0.865
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.780
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
 
 0.723
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.719
rpoC
DNA-directed RNA polymerase, beta'' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.695
AFG36819.1
Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
 
 0.665
AFG37156.1
PFAM: RNA polymerase Rpb6.
   
 
 0.662
AFG38676.1
CarD-like transcriptional regulator; PFAM: CarD-like/TRCF domain.
   
 
 0.642
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 
 0.638
AFG36944.1
Hypothetical protein; PFAM: Bacterial transcription activator, effector binding domain.
    
 
 0.635
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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