STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFG36885.1Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family. (268 aa)    
Predicted Functional Partners:
AFG36886.1
PFAM: Glycosyl hydrolase family 3 N terminal domain.
       0.791
glgA
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
       0.752
AFG36887.1
PFAM: FlgN protein.
       0.535
AFG36888.1
Flagellar hook-associated protein FlgK; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
       0.511
AFG36889.1
Flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
       0.511
csrA
Carbon storage regulator CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
       0.468
AFG36495.1
PFAM: Domain of unknown function (DUF1707).
 
     0.466
fliW
Hypothetical protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
       0.465
argR
Arginine repressor; Regulates arginine biosynthesis genes.
 
     0.443
AFG38682.1
PFAM: Predicted membrane protein (DUF2154); Domain of unknown function (DUF1707).
 
     0.426
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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