STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFG37448.1Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase, putative. (1491 aa)    
Predicted Functional Partners:
AFG37413.1
Putative membrane protein; PFAM: Protein of unknown function (DUF1113).
 
     0.784
AFG36225.1
CoA-substrate-specific enzyme activase, putative; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase, putative.
 
   
0.673
AFG37447.1
Superfamily II DNA helicase; PFAM: DEAD/DEAH box helicase.
       0.575
AFG38482.1
Alcohol dehydrogenase, class IV; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.563
AFG38051.1
PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.501
AFG36332.1
Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase.
   
  
 0.404
AFG37391.1
Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase.
   
  
 0.404
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
Server load: low (24%) [HD]