node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFG37193.1 | AFG37989.1 | Spiaf_1106 | Spiaf_1938 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | 0.929 |
AFG37193.1 | AFG38843.1 | Spiaf_1106 | Spiaf_2819 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Cytidyltransferase-related enzyme; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 0.935 |
AFG37193.1 | AFG38857.1 | Spiaf_1106 | Spiaf_2833 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.959 |
AFG37193.1 | nadD | Spiaf_1106 | Spiaf_1881 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.945 |
AFG37193.1 | nadE | Spiaf_1106 | Spiaf_2805 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.675 |
AFG37243.1 | AFG38750.1 | Spiaf_1164 | Spiaf_2725 | PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | PFAM: Shikimate dehydrogenase substrate binding domain; Type I 3-dehydroquinase; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; 3-dehydroquinate dehydratase, type I. | 0.572 |
AFG37243.1 | nadD | Spiaf_1164 | Spiaf_1881 | PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.954 |
AFG37243.1 | rsfS | Spiaf_1164 | Spiaf_1879 | PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.594 |
AFG37989.1 | AFG37193.1 | Spiaf_1938 | Spiaf_1106 | PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.929 |
AFG37989.1 | AFG38843.1 | Spiaf_1938 | Spiaf_2819 | PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Cytidyltransferase-related enzyme; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 0.917 |
AFG37989.1 | AFG38857.1 | Spiaf_1938 | Spiaf_2833 | PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.918 |
AFG37989.1 | nadD | Spiaf_1938 | Spiaf_1881 | PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.967 |
AFG37989.1 | nadE | Spiaf_1938 | Spiaf_2805 | PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.470 |
AFG38598.1 | AFG38843.1 | Spiaf_2568 | Spiaf_2819 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Cytidyltransferase-related enzyme; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 0.959 |
AFG38598.1 | nadD | Spiaf_2568 | Spiaf_1881 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.936 |
AFG38598.1 | nadE | Spiaf_2568 | Spiaf_2805 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.944 |
AFG38598.1 | nadK | Spiaf_2568 | Spiaf_2131 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.924 |
AFG38750.1 | AFG37243.1 | Spiaf_2725 | Spiaf_1164 | PFAM: Shikimate dehydrogenase substrate binding domain; Type I 3-dehydroquinase; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; 3-dehydroquinate dehydratase, type I. | PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | 0.572 |
AFG38750.1 | nadD | Spiaf_2725 | Spiaf_1881 | PFAM: Shikimate dehydrogenase substrate binding domain; Type I 3-dehydroquinase; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; 3-dehydroquinate dehydratase, type I. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.944 |
AFG38750.1 | nadK | Spiaf_2725 | Spiaf_2131 | PFAM: Shikimate dehydrogenase substrate binding domain; Type I 3-dehydroquinase; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; 3-dehydroquinate dehydratase, type I. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.452 |