node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFG38177.1 | AFG38178.1 | Spiaf_2129 | Spiaf_2130 | Hypothetical protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.739 |
AFG38177.1 | nadK | Spiaf_2129 | Spiaf_2131 | Hypothetical protein. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.739 |
AFG38178.1 | AFG38177.1 | Spiaf_2130 | Spiaf_2129 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein. | 0.739 |
AFG38178.1 | nadK | Spiaf_2130 | Spiaf_2131 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.956 |
AFG38598.1 | AFG38811.1 | Spiaf_2568 | Spiaf_2787 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.903 |
AFG38598.1 | AFG38812.1 | Spiaf_2568 | Spiaf_2788 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Hypothetical protein. | 0.905 |
AFG38598.1 | AFG38813.1 | Spiaf_2568 | Spiaf_2789 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | NAD/NADP transhydrogenase alpha subunit; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: NAD(P) transhydrogenase, alpha subunit. | 0.905 |
AFG38598.1 | AFG38843.1 | Spiaf_2568 | Spiaf_2819 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Cytidyltransferase-related enzyme; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 0.959 |
AFG38598.1 | AFG38879.1 | Spiaf_2568 | Spiaf_2855 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Zn-finger containing NTP pyrophosphohydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. | 0.922 |
AFG38598.1 | nadD | Spiaf_2568 | Spiaf_1881 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.936 |
AFG38598.1 | nadE | Spiaf_2568 | Spiaf_2805 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.944 |
AFG38598.1 | nadK | Spiaf_2568 | Spiaf_2131 | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.924 |
AFG38811.1 | AFG38598.1 | Spiaf_2787 | Spiaf_2568 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. | 0.903 |
AFG38811.1 | AFG38812.1 | Spiaf_2787 | Spiaf_2788 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Hypothetical protein. | 0.999 |
AFG38811.1 | AFG38813.1 | Spiaf_2787 | Spiaf_2789 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD/NADP transhydrogenase alpha subunit; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: NAD(P) transhydrogenase, alpha subunit. | 0.999 |
AFG38811.1 | AFG38843.1 | Spiaf_2787 | Spiaf_2819 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Cytidyltransferase-related enzyme; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 0.900 |
AFG38811.1 | AFG38879.1 | Spiaf_2787 | Spiaf_2855 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Zn-finger containing NTP pyrophosphohydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. | 0.900 |
AFG38811.1 | nadD | Spiaf_2787 | Spiaf_1881 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
AFG38811.1 | nadE | Spiaf_2787 | Spiaf_2805 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.930 |
AFG38811.1 | nadK | Spiaf_2787 | Spiaf_2131 | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.907 |