STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFG38757.1DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Belongs to the FtsK/SpoIIIE/SftA family. (886 aa)    
Predicted Functional Partners:
AFG38166.1
Cell division septal protein; Essential cell division protein.
  
 
 0.797
AFG38759.1
PFAM: Hsp70 protein.
  
  
 0.735
AFG38758.1
Soluble lytic murein transglycosylase-like protein; PFAM: Transglycosylase SLT domain.
     
 0.726
AFG38887.1
Putative transcriptional regulator; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.
  
   
 0.694
AFG36781.1
Subtilisin-like serine protease; PFAM: Subtilase family.
  
 
 0.667
ruvB
Holliday junction DNA helicase, RuvB subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
  
 0.658
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.619
xerC
Site-specific recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
   
 0.613
mraZ
PFAM: MraZ protein; TIGRFAM: mraZ protein; manually curated; Belongs to the MraZ family.
 
  
 0.611
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.606
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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