node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFV40422.1 | SFV41106.1 | LAC1533_1002 | LAC1533_1685 | Single-stranded-DNA-specific exonuclease RecJ. | ATP-dependent DNA helicase UvrD/PcrA. | 0.639 |
SFV40422.1 | polA | LAC1533_1002 | LAC1533_0970 | Single-stranded-DNA-specific exonuclease RecJ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.656 |
SFV40422.1 | radA | LAC1533_1002 | LAC1533_1705 | Single-stranded-DNA-specific exonuclease RecJ. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.631 |
SFV40422.1 | radC | LAC1533_1002 | LAC1533_1403 | Single-stranded-DNA-specific exonuclease RecJ. | DNA repair protein RadC; Belongs to the UPF0758 family. | 0.448 |
SFV40422.1 | recA | LAC1533_1002 | LAC1533_1540 | Single-stranded-DNA-specific exonuclease RecJ. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.605 |
SFV40422.1 | recX | LAC1533_1002 | LAC1533_1595 | Single-stranded-DNA-specific exonuclease RecJ. | Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family. | 0.612 |
SFV41106.1 | SFV40422.1 | LAC1533_1685 | LAC1533_1002 | ATP-dependent DNA helicase UvrD/PcrA. | Single-stranded-DNA-specific exonuclease RecJ. | 0.639 |
SFV41106.1 | metG | LAC1533_1685 | LAC1533_0729 | ATP-dependent DNA helicase UvrD/PcrA. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.403 |
SFV41106.1 | polA | LAC1533_1685 | LAC1533_0970 | ATP-dependent DNA helicase UvrD/PcrA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.825 |
SFV41106.1 | radA | LAC1533_1685 | LAC1533_1705 | ATP-dependent DNA helicase UvrD/PcrA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.677 |
SFV41106.1 | recA | LAC1533_1685 | LAC1533_1540 | ATP-dependent DNA helicase UvrD/PcrA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.886 |
SFV41125.1 | SFV41127.1 | LAC1533_1704 | LAC1533_1706 | PilT family ATPase; Membrane-associated protein containing RNA-binding TRAM domain and ribonuclease PIN-domain, YacL B.subtilis ortholog. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.517 |
SFV41125.1 | gltX | LAC1533_1704 | LAC1533_1703 | PilT family ATPase; Membrane-associated protein containing RNA-binding TRAM domain and ribonuclease PIN-domain, YacL B.subtilis ortholog. | Glutamyl-tRNA synthetase @ Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.672 |
SFV41125.1 | radA | LAC1533_1704 | LAC1533_1705 | PilT family ATPase; Membrane-associated protein containing RNA-binding TRAM domain and ribonuclease PIN-domain, YacL B.subtilis ortholog. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.784 |
SFV41127.1 | SFV41125.1 | LAC1533_1706 | LAC1533_1704 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | PilT family ATPase; Membrane-associated protein containing RNA-binding TRAM domain and ribonuclease PIN-domain, YacL B.subtilis ortholog. | 0.517 |
SFV41127.1 | gltX | LAC1533_1706 | LAC1533_1703 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Glutamyl-tRNA synthetase @ Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.635 |
SFV41127.1 | polA | LAC1533_1706 | LAC1533_0970 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.603 |
SFV41127.1 | radA | LAC1533_1706 | LAC1533_1705 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.756 |
SFV41127.1 | recA | LAC1533_1706 | LAC1533_1540 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.442 |
gltX | SFV41125.1 | LAC1533_1703 | LAC1533_1704 | Glutamyl-tRNA synthetase @ Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | PilT family ATPase; Membrane-associated protein containing RNA-binding TRAM domain and ribonuclease PIN-domain, YacL B.subtilis ortholog. | 0.672 |