SFV41243.1 protein (Lactobacillus acidipiscis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SFV41243.1

Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1). (541 aa)

Predicted Functional Partners:

SFV41242.1

0.992

SFV41241.1

0.991

SFV41240.1

0.989

SFV41239.1

0.986

LAC1533_0144

0.905

SFV39749.1

0.902

SFV39815.1

0.902

SFV39893.1

0.902

SFV39720.1

0.412

Your Current Organism:

Lactobacillus acidipiscis

NCBI taxonomy Id: 89059
Other names: CCUG 42961 [[Lactobacillus cypricasei]], CCUG 46556, CIP 106393 [[Lactobacillus cypricasei]], CIP 106750, DSM 15353 [[Lactobacillus cypricasei]], DSM 15836, JCM 10692, KCTC 13900 [[Lactobacillus cypricasei]], L. acidipiscis, Lactobacillus acidipiscis Tanasupawat et al. 2000, Lactobacillus cypricasei, Lactobacillus cypricasei Lawson et al. 2001, Lactobacillus sp. FS60-1, Lactobacillus sp. FS60-1T, Lactobacillus sp. LMG 17676, Lactobacillus sp. LMK3, NBRC 102163, NRIC 0300, PCU 207, PCU:207, strain FS60-1, strain LMK3 [[Lactobacillus cypricasei]]

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LAC1533_0144	SFV39720.1	LAC1533_0144	LAC1533_0300	ABC transporter periplasmic protein.	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	0.412
LAC1533_0144	SFV39749.1	LAC1533_0144	LAC1533_0329	ABC transporter periplasmic protein.	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.908
LAC1533_0144	SFV39815.1	LAC1533_0144	LAC1533_0395	ABC transporter periplasmic protein.	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.908
LAC1533_0144	SFV39893.1	LAC1533_0144	LAC1533_0473	ABC transporter periplasmic protein.	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.907
LAC1533_0144	SFV41239.1	LAC1533_0144	LAC1533_1816	ABC transporter periplasmic protein.	Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1).	0.975
LAC1533_0144	SFV41240.1	LAC1533_0144	LAC1533_1817	ABC transporter periplasmic protein.	Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1); Belongs to the ABC transporter superfamily.	0.980
LAC1533_0144	SFV41241.1	LAC1533_0144	LAC1533_1818	ABC transporter periplasmic protein.	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	0.984
LAC1533_0144	SFV41242.1	LAC1533_0144	LAC1533_1819	ABC transporter periplasmic protein.	Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1).	0.985
LAC1533_0144	SFV41243.1	LAC1533_0144	LAC1533_1820	ABC transporter periplasmic protein.	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.905
SFV39720.1	LAC1533_0144	LAC1533_0300	LAC1533_0144	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	ABC transporter periplasmic protein.	0.412
SFV39720.1	SFV39749.1	LAC1533_0300	LAC1533_0329	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.412
SFV39720.1	SFV39815.1	LAC1533_0300	LAC1533_0395	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.412
SFV39720.1	SFV39893.1	LAC1533_0300	LAC1533_0473	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.450
SFV39720.1	SFV41239.1	LAC1533_0300	LAC1533_1816	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1).	0.812
SFV39720.1	SFV41240.1	LAC1533_0300	LAC1533_1817	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1); Belongs to the ABC transporter superfamily.	0.924
SFV39720.1	SFV41241.1	LAC1533_0300	LAC1533_1818	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	0.931
SFV39720.1	SFV41243.1	LAC1533_0300	LAC1533_1820	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.412
SFV39749.1	LAC1533_0144	LAC1533_0329	LAC1533_0144	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	ABC transporter periplasmic protein.	0.908
SFV39749.1	SFV39720.1	LAC1533_0329	LAC1533_0300	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1).	0.412
SFV39749.1	SFV39815.1	LAC1533_0329	LAC1533_0395	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1).	0.903

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Network Stats

number of nodes:

4

number of edges:

3

average node degree:

1.5

avg. local clustering coefficient:

0.75

expected number of edges:

3

PPI enrichment p-value:

0.565

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006383

Transcription by RNA polymerase III

8 of 25

2.29

6.02

7.19e-14

GO:0006384

Transcription initiation from RNA polymerase III promoter

5 of 8

2.59

4.44

2.90e-09

GO:0042791

5S class rRNA transcription by RNA polymerase III

4 of 4

2.79

3.81

8.35e-08

GO:0098781

ncRNA transcription

6 of 45

1.91

3.28

2.10e-08

GO:0006351

Transcription, DNA-templated

10 of 191

1.51

2.91

7.87e-12

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000995

RNA polymerase III general transcription initiation factor activity

2 of 3

2.61

0.96

0.0181

GO:0003677

DNA binding

7 of 530

0.91

0.64

0.0071

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0090576

RNA polymerase III transcription regulator complex

6 of 7

2.72

5.9

4.87e-12

GO:0000127

Transcription factor TFIIIC complex

4 of 5

2.69

3.58

1.96e-07

GO:0005666

RNA polymerase III complex

4 of 17

2.16

2.66

4.60e-06

GO:0000126

Transcription factor TFIIIB complex

2 of 2

2.79

1.55

0.0015

GO:0032991

Protein-containing complex

10 of 1845

0.52

0.41

0.0018

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1092

RNA Polymerase III Transcription, and RNA polymerase I complex

11 of 33

2.31

8.95

2.72e-22

CL:1147

5S class rRNA transcription by RNA polymerase III

5 of 5

2.79

5.18

1.71e-10

CL:1094

RNA polymerase III complex, and RNA Polymerase I Transcription Initiation

6 of 26

2.15

4.28

4.71e-10

CL:1097

RNA polymerase III complex

4 of 12

2.31

3.07

9.26e-07

CL:1099

RNA polymerase III complex

3 of 7

2.42

2.29

4.67e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

4 of 39

1.8

1.92

6.39e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76066

RNA Polymerase III Transcription Initiation From Type 2 Promoter

10 of 26

2.37

8.52

4.52e-20

MAP-76061

RNA Polymerase III Transcription Initiation From Type 1 Promoter

10 of 26

2.37

8.52

4.52e-20

MAP-76046

RNA Polymerase III Transcription Initiation

10 of 26

2.37

8.52

4.52e-20

MAP-74158

RNA Polymerase III Transcription

10 of 26

2.37

8.52

4.52e-20

MAP-74160

Gene expression (Transcription)

10 of 477

1.11

1.48

6.30e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

4 of 77

1.51

1.02

0.0057

GOCC:0005666

RNA polymerase III complex

2 of 6

2.31

0.91

0.0216

GOCC:0032991

Protein-containing complex

10 of 2101

0.47

0.32

0.0216

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0396

Initiation factor

6 of 45

1.91

3.33

1.44e-08

KW-0240

DNA-directed RNA polymerase

2 of 16

1.89

0.81

0.0288

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