node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG76236.1 | SDH28580.1 | SAMN05216605_10380 | SAMN05216605_105293 | Glutamate synthase (NADPH) large subunit. | Homoserine dehydrogenase. | 0.851 |
SDG76236.1 | SDI63523.1 | SAMN05216605_10380 | SAMN05216605_11597 | Glutamate synthase (NADPH) large subunit. | Branched chain amino acid aminotransferase apoenzyme. | 0.503 |
SDG76236.1 | SDI94633.1 | SAMN05216605_10380 | SAMN05216605_11975 | Glutamate synthase (NADPH) large subunit. | Aminodeoxychorismate lyase apoprotein. | 0.503 |
SDG76236.1 | SDJ44882.1 | SAMN05216605_10380 | SAMN05216605_13032 | Glutamate synthase (NADPH) large subunit. | Acetolactate synthase, large subunit. | 0.597 |
SDG76236.1 | ilvC | SAMN05216605_10380 | SAMN05216605_13034 | Glutamate synthase (NADPH) large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.789 |
SDG76236.1 | ilvD | SAMN05216605_10380 | SAMN05216605_104265 | Glutamate synthase (NADPH) large subunit. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.857 |
SDG76236.1 | leuA | SAMN05216605_10380 | SAMN05216605_105324 | Glutamate synthase (NADPH) large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.515 |
SDG76236.1 | leuB | SAMN05216605_10380 | SAMN05216605_107286 | Glutamate synthase (NADPH) large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.909 |
SDG76236.1 | leuC | SAMN05216605_10380 | SAMN05216605_107288 | Glutamate synthase (NADPH) large subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.746 |
SDG76236.1 | leuC-2 | SAMN05216605_10380 | SAMN05216605_11116 | Glutamate synthase (NADPH) large subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.747 |
SDH28580.1 | SDG76236.1 | SAMN05216605_105293 | SAMN05216605_10380 | Homoserine dehydrogenase. | Glutamate synthase (NADPH) large subunit. | 0.851 |
SDH28580.1 | SDI63523.1 | SAMN05216605_105293 | SAMN05216605_11597 | Homoserine dehydrogenase. | Branched chain amino acid aminotransferase apoenzyme. | 0.970 |
SDH28580.1 | SDI94633.1 | SAMN05216605_105293 | SAMN05216605_11975 | Homoserine dehydrogenase. | Aminodeoxychorismate lyase apoprotein. | 0.970 |
SDH28580.1 | SDJ44882.1 | SAMN05216605_105293 | SAMN05216605_13032 | Homoserine dehydrogenase. | Acetolactate synthase, large subunit. | 0.994 |
SDH28580.1 | ilvC | SAMN05216605_105293 | SAMN05216605_13034 | Homoserine dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.987 |
SDH28580.1 | ilvD | SAMN05216605_105293 | SAMN05216605_104265 | Homoserine dehydrogenase. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.892 |
SDH28580.1 | leuA | SAMN05216605_105293 | SAMN05216605_105324 | Homoserine dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.932 |
SDH28580.1 | leuB | SAMN05216605_105293 | SAMN05216605_107286 | Homoserine dehydrogenase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.961 |
SDH28580.1 | leuC | SAMN05216605_105293 | SAMN05216605_107288 | Homoserine dehydrogenase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.939 |
SDH28580.1 | leuC-2 | SAMN05216605_105293 | SAMN05216605_11116 | Homoserine dehydrogenase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.930 |