STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDH94862.1Fumarylacetoacetate hydrolase. (431 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 
 0.995
SDH95012.1
Maleylacetoacetate isomerase.
 
 0.979
SDH94975.1
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.897
SDI80943.1
Phenylalanine 4-hydroxylase.
 
  
 0.755
SDI30589.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.732
SDI81031.1
Aromatic amino acid aminotransferase apoenzyme.
  
 
 0.664
fumC-2
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.663
SDI80989.1
Pterin-4-alpha-carbinolamine dehydratase.
  
  
 0.662
SDH65949.1
Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.652
SDH94937.1
Transcriptional regulator, IclR family.
  
  
 0.649
Your Current Organism:
Pseudomonas abietaniphila
NCBI taxonomy Id: 89065
Other names: ATCC 700689, CCUG 50779, CIP 106708, P. abietaniphila, strain BKME-9
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