node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG18019.1 | SDI92795.1 | SAMN05216605_101350 | SAMN05216605_11924 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Spermidine synthase. | 0.755 |
SDG18019.1 | mtnC | SAMN05216605_101350 | SAMN05216605_111109 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.566 |
SDG18019.1 | speD | SAMN05216605_101350 | SAMN05216605_10411 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.780 |
SDG18019.1 | speE | SAMN05216605_101350 | SAMN05216605_111103 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Spermidine synthase /spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.795 |
SDG53051.1 | SDG64137.1 | SAMN05216605_102338 | SAMN05216605_102663 | Agmatinase; Belongs to the arginase family. | Protein N-acetyltransferase, RimJ/RimL family. | 0.600 |
SDG53051.1 | SDI44888.1 | SAMN05216605_102338 | SAMN05216605_113157 | Agmatinase; Belongs to the arginase family. | Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.710 |
SDG53051.1 | SDI92795.1 | SAMN05216605_102338 | SAMN05216605_11924 | Agmatinase; Belongs to the arginase family. | Spermidine synthase. | 0.720 |
SDG53051.1 | speA | SAMN05216605_102338 | SAMN05216605_103325 | Agmatinase; Belongs to the arginase family. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | 0.758 |
SDG53051.1 | speD | SAMN05216605_102338 | SAMN05216605_10411 | Agmatinase; Belongs to the arginase family. | Adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.614 |
SDG53051.1 | speE | SAMN05216605_102338 | SAMN05216605_111103 | Agmatinase; Belongs to the arginase family. | Spermidine synthase /spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.745 |
SDG64137.1 | SDG53051.1 | SAMN05216605_102663 | SAMN05216605_102338 | Protein N-acetyltransferase, RimJ/RimL family. | Agmatinase; Belongs to the arginase family. | 0.600 |
SDG64137.1 | SDH37617.1 | SAMN05216605_102663 | SAMN05216605_10687 | Protein N-acetyltransferase, RimJ/RimL family. | Agmatinase; Belongs to the arginase family. | 0.600 |
SDG64137.1 | SDI44888.1 | SAMN05216605_102663 | SAMN05216605_113157 | Protein N-acetyltransferase, RimJ/RimL family. | Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.633 |
SDG64137.1 | SDI92795.1 | SAMN05216605_102663 | SAMN05216605_11924 | Protein N-acetyltransferase, RimJ/RimL family. | Spermidine synthase. | 0.623 |
SDG64137.1 | speE | SAMN05216605_102663 | SAMN05216605_111103 | Protein N-acetyltransferase, RimJ/RimL family. | Spermidine synthase /spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.712 |
SDH37617.1 | SDG64137.1 | SAMN05216605_10687 | SAMN05216605_102663 | Agmatinase; Belongs to the arginase family. | Protein N-acetyltransferase, RimJ/RimL family. | 0.600 |
SDH37617.1 | SDI44888.1 | SAMN05216605_10687 | SAMN05216605_113157 | Agmatinase; Belongs to the arginase family. | Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.710 |
SDH37617.1 | SDI92795.1 | SAMN05216605_10687 | SAMN05216605_11924 | Agmatinase; Belongs to the arginase family. | Spermidine synthase. | 0.720 |
SDH37617.1 | speA | SAMN05216605_10687 | SAMN05216605_103325 | Agmatinase; Belongs to the arginase family. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | 0.758 |
SDH37617.1 | speD | SAMN05216605_10687 | SAMN05216605_10411 | Agmatinase; Belongs to the arginase family. | Adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.614 |