node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG75899.1 | SDG76236.1 | SAMN05216605_10370 | SAMN05216605_10380 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Glutamate synthase (NADPH) large subunit. | 0.537 |
SDG75899.1 | SDG78997.1 | SAMN05216605_10370 | SAMN05216605_103162 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.523 |
SDG75899.1 | SDH65806.1 | SAMN05216605_10370 | SAMN05216605_107258 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.523 |
SDG75899.1 | SDI08770.1 | SAMN05216605_10370 | SAMN05216605_110167 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Aspartate ammonia-lyase. | 0.659 |
SDG75899.1 | SDI09415.1 | SAMN05216605_10370 | SAMN05216605_110183 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Pyruvate carboxylase subunit B. | 0.845 |
SDG75899.1 | SDI30589.1 | SAMN05216605_10370 | SAMN05216605_11256 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.894 |
SDG75899.1 | pckA | SAMN05216605_10370 | SAMN05216605_12017 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.851 |
SDG75899.1 | sucC | SAMN05216605_10370 | SAMN05216605_107255 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.776 |
SDG75899.1 | sucD | SAMN05216605_10370 | SAMN05216605_107254 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.719 |
SDG76236.1 | SDG75899.1 | SAMN05216605_10380 | SAMN05216605_10370 | Glutamate synthase (NADPH) large subunit. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.537 |
SDG76236.1 | SDG78997.1 | SAMN05216605_10380 | SAMN05216605_103162 | Glutamate synthase (NADPH) large subunit. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.847 |
SDG76236.1 | SDH65806.1 | SAMN05216605_10380 | SAMN05216605_107258 | Glutamate synthase (NADPH) large subunit. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.847 |
SDG76236.1 | SDI09415.1 | SAMN05216605_10380 | SAMN05216605_110183 | Glutamate synthase (NADPH) large subunit. | Pyruvate carboxylase subunit B. | 0.884 |
SDG76236.1 | SDI30589.1 | SAMN05216605_10380 | SAMN05216605_11256 | Glutamate synthase (NADPH) large subunit. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.433 |
SDG76236.1 | maeA | SAMN05216605_10380 | SAMN05216605_105125 | Glutamate synthase (NADPH) large subunit. | NAD-dependent malic enzyme. | 0.537 |
SDG76236.1 | pckA | SAMN05216605_10380 | SAMN05216605_12017 | Glutamate synthase (NADPH) large subunit. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.850 |
SDG76236.1 | sucC | SAMN05216605_10380 | SAMN05216605_107255 | Glutamate synthase (NADPH) large subunit. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.853 |
SDG76236.1 | sucD | SAMN05216605_10380 | SAMN05216605_107254 | Glutamate synthase (NADPH) large subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.872 |
SDG78997.1 | SDG75899.1 | SAMN05216605_103162 | SAMN05216605_10370 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.523 |
SDG78997.1 | SDG76236.1 | SAMN05216605_103162 | SAMN05216605_10380 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glutamate synthase (NADPH) large subunit. | 0.847 |