node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEP67058.1 | guaA | SAMN04488558_101314 | SAMN04488558_1117 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.737 |
SEP67058.1 | purD | SAMN04488558_101314 | SAMN04488558_101317 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.998 |
SEP67058.1 | purE | SAMN04488558_101314 | SAMN04488558_101316 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
SEP67058.1 | purF | SAMN04488558_101314 | SAMN04488558_101321 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.997 |
SEP67058.1 | purH | SAMN04488558_101314 | SAMN04488558_101318 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | IMP cyclohydrolase. | 0.997 |
SEP67058.1 | purL | SAMN04488558_101314 | SAMN04488558_102106 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.983 |
SEP67058.1 | purM | SAMN04488558_101314 | SAMN04488558_101320 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.996 |
SEP67058.1 | purN | SAMN04488558_101314 | SAMN04488558_101319 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.997 |
SEP67058.1 | purQ | SAMN04488558_101314 | SAMN04488558_102107 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.979 |
SEP67058.1 | purS | SAMN04488558_101314 | SAMN04488558_102108 | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.955 |
guaA | SEP67058.1 | SAMN04488558_1117 | SAMN04488558_101314 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.737 |
guaA | purD | SAMN04488558_1117 | SAMN04488558_101317 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.912 |
guaA | purE | SAMN04488558_1117 | SAMN04488558_101316 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.668 |
guaA | purF | SAMN04488558_1117 | SAMN04488558_101321 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.785 |
guaA | purH | SAMN04488558_1117 | SAMN04488558_101318 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | IMP cyclohydrolase. | 0.914 |
guaA | purL | SAMN04488558_1117 | SAMN04488558_102106 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.901 |
guaA | purM | SAMN04488558_1117 | SAMN04488558_101320 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.637 |
guaA | purN | SAMN04488558_1117 | SAMN04488558_101319 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.597 |
guaA | purQ | SAMN04488558_1117 | SAMN04488558_102107 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.771 |
guaA | purS | SAMN04488558_1117 | SAMN04488558_102108 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.572 |