SEQ26520.1 protein (Ignavigranum ruoffiae) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

SEQ26520.1

ABC-2 type transport system ATP-binding protein. (313 aa)

Predicted Functional Partners:

SEQ26454.1

0.964

SEQ26492.1

0.964

SEQ26643.1

0.924

SEP62111.1

0.747

SEQ10486.1

0.747

SEQ40537.1

0.707

SEQ40573.1

0.706

SEP82472.1

0.696

SEQ27870.1

0.681

SEQ08223.1

0.656

Your Current Organism:

Ignavigranum ruoffiae

NCBI taxonomy Id: 89093
Other names: ATCC 700630, CCUG 37658, CIP 105896, DSM 15695, I. ruoffiae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SEP62111.1	SEQ26520.1	SAMN04488558_101212	SAMN04488558_10773	Hypothetical protein.	ABC-2 type transport system ATP-binding protein.	0.747
SEP82472.1	SEQ08223.1	SAMN04488558_102134	SAMN04488558_10520	Amino acid ABC transporter substrate-binding protein, PAAT family /amino acid ABC transporter membrane protein, PAAT family.	Amino acid/amide ABC transporter membrane protein 2, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.420
SEP82472.1	SEQ26520.1	SAMN04488558_102134	SAMN04488558_10773	Amino acid ABC transporter substrate-binding protein, PAAT family /amino acid ABC transporter membrane protein, PAAT family.	ABC-2 type transport system ATP-binding protein.	0.696
SEP82472.1	SEQ26643.1	SAMN04488558_102134	SAMN04488558_10776	Amino acid ABC transporter substrate-binding protein, PAAT family /amino acid ABC transporter membrane protein, PAAT family.	Putative ABC transport system ATP-binding protein.	0.884
SEP82472.1	SEQ27870.1	SAMN04488558_102134	SAMN04488558_107107	Amino acid ABC transporter substrate-binding protein, PAAT family /amino acid ABC transporter membrane protein, PAAT family.	Putative lysine transport system permease protein.	0.994
SEP82472.1	SEQ40537.1	SAMN04488558_102134	SAMN04488558_1102	Amino acid ABC transporter substrate-binding protein, PAAT family /amino acid ABC transporter membrane protein, PAAT family.	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains.	0.602
SEQ08223.1	SEP82472.1	SAMN04488558_10520	SAMN04488558_102134	Amino acid/amide ABC transporter membrane protein 2, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	Amino acid ABC transporter substrate-binding protein, PAAT family /amino acid ABC transporter membrane protein, PAAT family.	0.420
SEQ08223.1	SEQ26520.1	SAMN04488558_10520	SAMN04488558_10773	Amino acid/amide ABC transporter membrane protein 2, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	ABC-2 type transport system ATP-binding protein.	0.656
SEQ08223.1	SEQ27870.1	SAMN04488558_10520	SAMN04488558_107107	Amino acid/amide ABC transporter membrane protein 2, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	Putative lysine transport system permease protein.	0.420
SEQ10486.1	SEQ26520.1	SAMN04488558_10582	SAMN04488558_10773	Hypothetical protein.	ABC-2 type transport system ATP-binding protein.	0.747
SEQ26454.1	SEQ26492.1	SAMN04488558_10771	SAMN04488558_10772	ABC-2 family transporter protein.	ABC-2 family transporter protein.	0.950
SEQ26454.1	SEQ26520.1	SAMN04488558_10771	SAMN04488558_10773	ABC-2 family transporter protein.	ABC-2 type transport system ATP-binding protein.	0.964
SEQ26454.1	SEQ26643.1	SAMN04488558_10771	SAMN04488558_10776	ABC-2 family transporter protein.	Putative ABC transport system ATP-binding protein.	0.434
SEQ26454.1	SEQ40537.1	SAMN04488558_10771	SAMN04488558_1102	ABC-2 family transporter protein.	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains.	0.685
SEQ26454.1	SEQ40573.1	SAMN04488558_10771	SAMN04488558_1103	ABC-2 family transporter protein.	Signal transduction histidine kinase.	0.719
SEQ26492.1	SEQ26454.1	SAMN04488558_10772	SAMN04488558_10771	ABC-2 family transporter protein.	ABC-2 family transporter protein.	0.950
SEQ26492.1	SEQ26520.1	SAMN04488558_10772	SAMN04488558_10773	ABC-2 family transporter protein.	ABC-2 type transport system ATP-binding protein.	0.964
SEQ26492.1	SEQ26643.1	SAMN04488558_10772	SAMN04488558_10776	ABC-2 family transporter protein.	Putative ABC transport system ATP-binding protein.	0.434
SEQ26492.1	SEQ40537.1	SAMN04488558_10772	SAMN04488558_1102	ABC-2 family transporter protein.	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains.	0.656
SEQ26492.1	SEQ40573.1	SAMN04488558_10772	SAMN04488558_1103	ABC-2 family transporter protein.	Signal transduction histidine kinase.	0.686

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

48

PPI enrichment p-value:

0.0411

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006457

Protein folding

7 of 19

1.93

3.65

1.72e-09

GO:0009408

Response to heat

5 of 9

2.11

3.0

5.64e-07

GO:0042026

Protein refolding

2 of 3

2.18

0.82

0.0305

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005515

Protein binding

6 of 29

1.68

2.35

1.11e-06

GO:0051082

Unfolded protein binding

4 of 10

1.96

2.27

1.77e-05

GO:0016887

ATP hydrolysis activity

4 of 41

1.35

1.16

0.00099

GO:0031072

Heat shock protein binding

2 of 4

2.06

1.16

0.0063

GO:0030554

Adenyl nucleotide binding

10 of 294

0.89

0.94

1.51e-06

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 875

0.46

0.38

0.0010

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:398

Protein folding, and ATP-dependent peptidase activity

8 of 22

1.92

4.26

1.29e-11

CL:400

Stress response, and Protein folding chaperone

7 of 15

2.03

4.25

1.19e-10

CL:403

Stress response, and Protein folding chaperone

4 of 8

2.06

2.33

1.78e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0346

Stress response

5 of 7

2.21

3.47

7.84e-08

KW-0143

Chaperone

5 of 13

1.95

2.88

4.19e-07

KW-0677

Repeat

3 of 10

1.84

1.45

0.0011

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02861

Clp amino terminal domain, pathogenicity island component

2 of 2

2.36

0.76

0.0400

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003959

ATPase, AAA-type, core

3 of 7

1.99

1.2

0.0049

IPR041546

ClpA/ClpB, AAA lid domain

2 of 2

2.36

0.79

0.0352

IPR036869

Chaperone J-domain superfamily

2 of 3

2.18

0.79

0.0352

IPR036628

Clp, N-terminal domain superfamily

2 of 2

2.36

0.79

0.0352

IPR028299

ClpA/B, conserved site 2

2 of 2

2.36

0.79

0.0352

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01086

C-terminal, D2-small domain, of ClpB protein

2 of 4

2.06

0.87

0.0232

SM00271

DnaJ molecular chaperone homology domain

2 of 4

2.06

0.87

0.0232

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