| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00020 | ISM_04900 | ISM_00020 | ISM_04900 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | 0.753 |
| ISM_00020 | ISM_06020 | ISM_00020 | ISM_06020 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.703 |
| ISM_00020 | ISM_06040 | ISM_00020 | ISM_06040 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.770 |
| ISM_00020 | ISM_06100 | ISM_00020 | ISM_06100 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.910 |
| ISM_00020 | ISM_06675 | ISM_00020 | ISM_06675 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.778 |
| ISM_00020 | ISM_08180 | ISM_00020 | ISM_08180 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.768 |
| ISM_00020 | ISM_09586 | ISM_00020 | ISM_09586 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.778 |
| ISM_00020 | ISM_14700 | ISM_00020 | ISM_14700 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.978 |
| ISM_00020 | cysC | ISM_00020 | ISM_11065 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.910 |
| ISM_00020 | mdh | ISM_00020 | ISM_05055 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.941 |
| ISM_04900 | ISM_00020 | ISM_04900 | ISM_00020 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.753 |
| ISM_04900 | ISM_06020 | ISM_04900 | ISM_06020 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.703 |
| ISM_04900 | ISM_06040 | ISM_04900 | ISM_06040 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.952 |
| ISM_04900 | ISM_06100 | ISM_04900 | ISM_06100 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.956 |
| ISM_04900 | ISM_06675 | ISM_04900 | ISM_06675 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.885 |
| ISM_04900 | ISM_08180 | ISM_04900 | ISM_08180 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.625 |
| ISM_04900 | ISM_09586 | ISM_04900 | ISM_09586 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.885 |
| ISM_04900 | ISM_14700 | ISM_04900 | ISM_14700 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.989 |
| ISM_04900 | cysC | ISM_04900 | ISM_11065 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.434 |
| ISM_04900 | mdh | ISM_04900 | ISM_05055 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.812 |