Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_00020Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (112 aa)    
Predicted Functional Partners:
ISM_14700
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
  
 0.978
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.941
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
 0.910
cysC
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate.
    
 0.910
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
    
 0.778
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
    
 0.778
ISM_06040
Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
  
 
 0.770
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
    
 0.768
ISM_04900
Iron-sulfur cluster-binding protein; COG1145 Ferredoxin.
    
 0.753
ISM_06020
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.703
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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