| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_00050 | ISM_00055 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | COG1164 Oligoendopeptidase F. | 0.573 |
| ISM_00050 | ISM_02625 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Hypothetical protein; COG3232 5-carboxymethyl-2-hydroxymuconate isomerase. | 0.594 |
| ISM_00050 | ISM_02775 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | 0.749 |
| ISM_00050 | ISM_04010 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | 0.638 |
| ISM_00050 | ISM_04025 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Threonine aldolase, low-specificity; COG3616 Predicted amino acid aldolase or racemase. | 0.739 |
| ISM_00050 | ISM_07490 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Hypothetical protein; COG0684 Demethylmenaquinone methyltransferase. | 0.873 |
| ISM_00050 | ISM_09020 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Glycolate oxidase, iron-sulfur subunit; COG0247 Fe-S oxidoreductase. | 0.755 |
| ISM_00050 | ISM_09025 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Putative glycolate oxidase subunit protein; COG0277 FAD/FMN-containing dehydrogenases. | 0.741 |
| ISM_00050 | ISM_11130 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.550 |
| ISM_00050 | ISM_13840 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.646 |
| ISM_00055 | ISM_00050 | COG1164 Oligoendopeptidase F. | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.573 |
| ISM_02625 | ISM_00050 | Hypothetical protein; COG3232 5-carboxymethyl-2-hydroxymuconate isomerase. | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.594 |
| ISM_02625 | ISM_13840 | Hypothetical protein; COG3232 5-carboxymethyl-2-hydroxymuconate isomerase. | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.529 |
| ISM_02775 | ISM_00050 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.749 |
| ISM_02775 | ISM_04010 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | 0.666 |
| ISM_02775 | ISM_04025 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Threonine aldolase, low-specificity; COG3616 Predicted amino acid aldolase or racemase. | 0.850 |
| ISM_02775 | ISM_09020 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Glycolate oxidase, iron-sulfur subunit; COG0247 Fe-S oxidoreductase. | 0.852 |
| ISM_02775 | ISM_09025 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Putative glycolate oxidase subunit protein; COG0277 FAD/FMN-containing dehydrogenases. | 0.851 |
| ISM_02775 | ISM_11130 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.629 |
| ISM_04010 | ISM_00050 | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.638 |