| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00050 | ISM_00055 | ISM_00050 | ISM_00055 | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | COG1164 Oligoendopeptidase F. | 0.663 |
| ISM_00055 | ISM_00050 | ISM_00055 | ISM_00050 | COG1164 Oligoendopeptidase F. | Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.663 |
| ISM_00055 | ISM_04305 | ISM_00055 | ISM_04305 | COG1164 Oligoendopeptidase F. | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | 0.502 |
| ISM_00055 | ISM_05005 | ISM_00055 | ISM_05005 | COG1164 Oligoendopeptidase F. | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | 0.502 |
| ISM_00055 | ISM_06220 | ISM_00055 | ISM_06220 | COG1164 Oligoendopeptidase F. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.450 |
| ISM_00055 | ISM_07755 | ISM_00055 | ISM_07755 | COG1164 Oligoendopeptidase F. | COG1609 Transcriptional regulators. | 0.502 |
| ISM_00055 | ISM_08290 | ISM_00055 | ISM_08290 | COG1164 Oligoendopeptidase F. | Transcriptional regulatory protein; COG1609 Transcriptional regulators. | 0.502 |
| ISM_00055 | ISM_08560 | ISM_00055 | ISM_08560 | COG1164 Oligoendopeptidase F. | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | 0.502 |
| ISM_00055 | ISM_11355 | ISM_00055 | ISM_11355 | COG1164 Oligoendopeptidase F. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.450 |
| ISM_00055 | ISM_13030 | ISM_00055 | ISM_13030 | COG1164 Oligoendopeptidase F. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.508 |
| ISM_00055 | murI | ISM_00055 | ISM_14710 | COG1164 Oligoendopeptidase F. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.449 |
| ISM_04305 | ISM_00055 | ISM_04305 | ISM_00055 | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | COG1164 Oligoendopeptidase F. | 0.502 |
| ISM_04305 | ISM_06220 | ISM_04305 | ISM_06220 | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.450 |
| ISM_04305 | ISM_11355 | ISM_04305 | ISM_11355 | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.450 |
| ISM_05005 | ISM_00055 | ISM_05005 | ISM_00055 | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | COG1164 Oligoendopeptidase F. | 0.502 |
| ISM_05005 | ISM_06220 | ISM_05005 | ISM_06220 | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.450 |
| ISM_05005 | ISM_11355 | ISM_05005 | ISM_11355 | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.450 |
| ISM_06220 | ISM_00055 | ISM_06220 | ISM_00055 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG1164 Oligoendopeptidase F. | 0.450 |
| ISM_06220 | ISM_04305 | ISM_06220 | ISM_04305 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | 0.450 |
| ISM_06220 | ISM_05005 | ISM_06220 | ISM_05005 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators. | 0.450 |