STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_00255Tryptophan repressor binding protein; COG0655 Multimeric flavodoxin WrbA. (191 aa)    
Predicted Functional Partners:
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
     
  0.850
ISM_08015
COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).
 
  
 0.807
ISM_08800
NAD(P)H dehydrogenase, quinone family protein; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).
    
 0.661
ISM_08530
COG1652 Uncharacterized protein containing LysM domain.
   
  
 0.586
ISM_11845
COG1652 Uncharacterized protein containing LysM domain.
   
  
 0.586
ISM_00250
COG1733 Predicted transcriptional regulators.
       0.583
ISM_13030
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.555
ISM_07825
Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 
 0.548
ISM_12595
Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 
 0.548
ISM_02335
Methyltransferase, UbiE/COQ5 family protein; COG0500 SAM-dependent methyltransferases.
     
  0.529
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (18%) [HD]