Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_00285COG2315 Uncharacterized protein conserved in bacteria. (121 aa)    
Predicted Functional Partners:
ISM_13015
Hypothetical protein.
  
  
 0.604
ISM_00280
Sensor histidine kinase of two-component; COG2202 FOG: PAS/PAC domain.
 
     0.573
ISM_07990
Hypothetical protein.
  
     0.467
ISM_00810
Possible endonuclease/exonuclease/phosphatase family protein.
 
     0.425
ISM_11250
Hypothetical protein; COG0464 ATPases of the AAA+ class.
  
     0.409
ISM_12890
Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.
  
     0.401
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (22%) [HD]