Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ISM_00325Hypothetical protein; COG0523 Putative GTPases (G3E family). (406 aa)    
Predicted Functional Partners:
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.755
rpsN
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.689
folE2
Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
 0.671
dksA
dnaK suppressor protein, putative; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
  
  
 0.597
rpmB
COG0227 Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.568
ISM_12640
precorrin-6Y C5,15-methyltransferase (decarboxylating); COG2241 Precorrin-6B methylase 1.
     
 0.526
rpmG
COG0267 Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
 
  
 0.500
ISM_00060
C4-type zinc finger protein, DksA/TraR family protein; COG1734 DnaK suppressor protein.
  
  
 0.493
ISM_05645
Hypothetical protein; COG3443 Predicted periplasmic or secreted protein.
  
  
 0.435
ISM_12610
Cobaltochelatase; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.
  
  
 0.426
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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