Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_00465Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). (434 aa)    
Predicted Functional Partners:
ISM_00460
COG0174 Glutamine synthetase.
 
 
  0.948
ISM_00450
COG0174 Glutamine synthetase.
 
 
  0.818
ISM_00455
COG0518 GMP synthase - Glutamine amidotransferase domain.
 
     0.810
ISM_12990
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
 
 0.808
ISM_09661
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
 
 0.806
ISM_09346
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
 
 0.804
ISM_07875
Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
  0.754
ISM_12585
COG1012 NAD-dependent aldehyde dehydrogenases.
  
 
  0.668
ISM_17060
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
  0.664
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
  
 
 0.616
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (18%) [HD]