Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_00490COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. (325 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.873
ISM_08755
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
     
 0.863
ISM_13135
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
     
 0.855
ISM_13065
Renal dipeptidase family protein; COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog.
 
    0.839
ISM_10526
COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.777
ISM_05425
Peptidase, M19 family protein; COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog.
  
    0.772
ISM_00500
COG4591 ABC-type transport system, involved in lipoprotein release, permease component.
       0.718
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
    
 0.697
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
    
 0.697
lolD
Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
       0.677
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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