| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00490 | ISM_00500 | ISM_00490 | ISM_00500 | COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | 0.725 |
| ISM_00490 | ISM_00505 | ISM_00490 | ISM_00505 | COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | prolyl-tRNA synthetase. | 0.543 |
| ISM_00490 | lolD | ISM_00490 | ISM_00495 | COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | 0.677 |
| ISM_00490 | proS | ISM_00490 | ISM_00510 | COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.418 |
| ISM_00500 | ISM_00490 | ISM_00500 | ISM_00490 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.725 |
| ISM_00500 | ISM_00505 | ISM_00500 | ISM_00505 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | prolyl-tRNA synthetase. | 0.645 |
| ISM_00500 | ISM_03315 | ISM_00500 | ISM_03315 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | Proton transporter TolQ; COG0811 Biopolymer transport proteins. | 0.716 |
| ISM_00500 | ISM_10136 | ISM_00500 | ISM_10136 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | Putative outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.964 |
| ISM_00500 | ISM_11870 | ISM_00500 | ISM_11870 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | Lipoprotein, putative. | 0.896 |
| ISM_00500 | bamA | ISM_00500 | ISM_15045 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | Outer membrane protein, OMP85 family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.765 |
| ISM_00500 | lolD | ISM_00500 | ISM_00495 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | 0.999 |
| ISM_00500 | pal | ISM_00500 | ISM_03295 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.759 |
| ISM_00500 | proS | ISM_00500 | ISM_00510 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.698 |
| ISM_00500 | tolB | ISM_00500 | ISM_03300 | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | Translocation protein TolB precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.685 |
| ISM_00505 | ISM_00490 | ISM_00505 | ISM_00490 | prolyl-tRNA synthetase. | COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.543 |
| ISM_00505 | ISM_00500 | ISM_00505 | ISM_00500 | prolyl-tRNA synthetase. | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | 0.645 |
| ISM_00505 | lolD | ISM_00505 | ISM_00495 | prolyl-tRNA synthetase. | Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | 0.606 |
| ISM_00505 | proS | ISM_00505 | ISM_00510 | prolyl-tRNA synthetase. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.652 |
| ISM_03315 | ISM_00500 | ISM_03315 | ISM_00500 | Proton transporter TolQ; COG0811 Biopolymer transport proteins. | COG4591 ABC-type transport system, involved in lipoprotein release, permease component. | 0.716 |
| ISM_03315 | bamA | ISM_03315 | ISM_15045 | Proton transporter TolQ; COG0811 Biopolymer transport proteins. | Outer membrane protein, OMP85 family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.743 |