Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_00540Endonuclease/exonuclease/phosphatase family protein. (340 aa)    
Predicted Functional Partners:
ISM_00545
Putative heat shock protein DnaJ; COG1076 DnaJ-domain-containing proteins 1.
       0.844
ISM_00535
Hypothetical protein.
 
     0.710
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.680
ISM_15820
Hypothetical protein; COG2995 Uncharacterized paraquat-inducible protein A.
  
     0.669
ISM_00555
Hypothetical protein.
       0.663
ISM_00550
Putative acetyltransferase, GNAT family protein; COG1247 Sortase and related acyltransferases.
       0.659
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.658
ISM_15650
Autoinducer-binding transcriptional regulator, LuxR family protein; COG2771 DNA-binding HTH domain-containing proteins.
  
     0.621
ISM_02485
Hypothetical protein; COG1372 Intein/homing endonuclease.
  
  
  0.619
ISM_02070
Hypothetical protein.
  
     0.614
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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