Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_00650Transcriptional regulatory protein; COG3284 Transcriptional activator of acetoin/glycerol metabolism. (317 aa)    
Predicted Functional Partners:
ISM_00645
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 
   0.840
ISM_11185
C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
     0.830
ISM_04850
COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
     0.784
ISM_16625
Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
      0.770
ISM_09291
Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
     0.677
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
 0.534
ISM_16955
Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
 0.534
ISM_05245
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.507
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
       0.494
acpS
4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
  
    0.432
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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