Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sfsACOG1489 DNA-binding protein, stimulates sugar fermentation; Belongs to the SfsA family. (234 aa)    
Predicted Functional Partners:
ISM_07290
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
 
    0.932
ISM_00670
Molybdenum cofactor biosynthesis domain protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA.
       0.705
ISM_00675
Acetyltransferase, GNAT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
       0.705
ISM_00680
Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.698
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.665
ISM_00685
OmpA domain protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.
       0.641
ISM_03250
Hypothetical protein; COG3279 Response regulator of the LytR/AlgR family.
    
   0.439
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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