STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_00795Haloacid dehalogenase, type II; COG1011 Predicted hydrolase (HAD superfamily). (228 aa)    
Predicted Functional Partners:
ISM_00800
Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
  0.876
ISM_00810
Possible endonuclease/exonuclease/phosphatase family protein.
       0.802
ISM_00815
3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
  0.798
ISM_08590
ephB, putative; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
   
 
 0.794
ISM_00805
COG1171 Threonine dehydratase.
       0.789
ISM_13030
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.777
ISM_09411
Hypothetical protein.
    
   0.653
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.610
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.585
ISM_04010
Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
 
  
  0.572
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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