Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_00810Possible endonuclease/exonuclease/phosphatase family protein. (401 aa)    
Predicted Functional Partners:
ISM_00815
3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
   
 0.810
ISM_00795
Haloacid dehalogenase, type II; COG1011 Predicted hydrolase (HAD superfamily).
       0.807
ISM_00800
Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
     
 0.806
ISM_00805
COG1171 Threonine dehydratase.
     
 0.745
ISM_11270
Hypothetical protein.
  
     0.672
ISM_11245
Hypothetical protein.
  
     0.653
ISM_04725
Hypothetical protein; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.
  
     0.652
ISM_11275
Hypothetical protein; COG1196 Chromosome segregation ATPases.
  
     0.637
ISM_07310
NifS-related protein; COG0520 Selenocysteine lyase.
    
   0.619
ISM_12170
Aminotransferase, class V; COG0520 Selenocysteine lyase.
    
   0.619
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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