Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_008153-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (266 aa)    
Predicted Functional Partners:
pcaC
4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
 0.984
ISM_12060
COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
  
 0.858
ISM_00800
Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
     0.844
ISM_00810
Possible endonuclease/exonuclease/phosphatase family protein.
 
   
 0.810
ISM_00795
Haloacid dehalogenase, type II; COG1011 Predicted hydrolase (HAD superfamily).
  
 
  0.784
ISM_00805
COG1171 Threonine dehydratase.
       0.743
pcaH
COG3485 Protocatechuate 3,4-dioxygenase beta subunit.
 
  
 0.723
ISM_00820
Oxidoreductase, zinc-binding dehydrogenase family protein; COG1062 Zn-dependent alcohol dehydrogenases, class III.
   
  0.689
ISM_10960
4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
 0.685
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.684
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.