Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_00820Oxidoreductase, zinc-binding dehydrogenase family protein; COG1062 Zn-dependent alcohol dehydrogenases, class III. (361 aa)    
Predicted Functional Partners:
ISM_08725
S-formylglutathione hydrolase, putative; Serine hydrolase involved in the detoxification of formaldehyde.
 0.992
ISM_11415
Hypothetical protein; COG1454 Alcohol dehydrogenase, class IV.
    
 0.859
ISM_00825
Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
     0.752
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
  0.705
ISM_00815
3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
   
  0.689
ISM_00800
Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
   
  0.670
ISM_09180
COG1012 NAD-dependent aldehyde dehydrogenases.
  
 0.662
ISM_08590
ephB, putative; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
    
  0.646
ISM_00790
Oxidoreductase, zinc-binding dehydrogenase family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
 
 
 0.618
ISM_00810
Possible endonuclease/exonuclease/phosphatase family protein.
       0.590
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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