Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_00825Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (417 aa)    
Predicted Functional Partners:
ISM_06470
Hypothetical protein; COG3734 2-keto-3-deoxy-galactonokinase.
  
 
 0.824
ISM_00820
Oxidoreductase, zinc-binding dehydrogenase family protein; COG1062 Zn-dependent alcohol dehydrogenases, class III.
 
     0.752
ISM_13245
Putative mandelate racemase/muconate lactonizing enzyme; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.
  
  
  0.707
ISM_11950
COG3239 Fatty acid desaturase.
  
     0.608
ISM_01065
Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.
   
   0.581
ISM_00795
Haloacid dehalogenase, type II; COG1011 Predicted hydrolase (HAD superfamily).
 
     0.562
ISM_06310
COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
     
  0.531
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
  0.531
ISM_13845
COG0698 Ribose 5-phosphate isomerase RpiB.
     
  0.531
ISM_00425
Hypothetical protein; COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component.
  
    0.505
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (14%) [HD]