STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_00835Hypothetical protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (269 aa)    
Predicted Functional Partners:
ISM_06245
Alkylphosphonate utilization protein PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.
  
 
 0.937
ISM_00840
Hydrolase, TatD family protein; COG0084 Mg-dependent DNase.
 
   
 0.871
ISM_00830
Malonate transporter, putative; COG0679 Predicted permeases.
       0.853
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.800
ISM_00845
DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.
     
 0.799
ISM_00855
COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
       0.798
ISM_00860
Lipoprotein, putative; COG3087 Cell division protein.
       0.749
lipB
Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
    
 0.642
ISM_06235
Alkylphosphonate utilization protein PhnL; COG4778 ABC-type phosphonate transport system, ATPase component.
  
  
 0.586
ISM_11795
Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family.
      0.581
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.