Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_01025Endoribonuclease L-PSP family protein; COG0251 Putative translation initiation inhibitor, yjgF family. (113 aa)    
Predicted Functional Partners:
ISM_01030
Probable pyridine nucleotide-disulphide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
 
    0.843
ISM_01040
Nopaline dehydrogenase, putative; COG0665 Glycine/D-amino acid oxidases (deaminating).
 
    0.822
ISM_01035
Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
 
    0.819
ISM_01045
Probable DctP (periplasmic C4-dicarboxylate binding protein); COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
 
     0.657
ISM_08755
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
   
  0.654
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.601
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
   0.584
ISM_01055
Probable DctQ (C4-dicarboxylate permease, small subunit); COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.
 
     0.571
ISM_07130
Proteinase; COG0693 Putative intracellular protease/amidase.
   
   0.529
ISM_01050
Probable DctM (C4-dicarboxylate permease, large subunit); COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.
 
     0.510
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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