| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01065 | ISM_01070 | ISM_01065 | ISM_01070 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Hypothetical protein. | 0.815 |
| ISM_01065 | ISM_02380 | ISM_01065 | ISM_02380 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.407 |
| ISM_01065 | ISM_03370 | ISM_01065 | ISM_03370 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Probable acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.407 |
| ISM_01065 | ISM_03375 | ISM_01065 | ISM_03375 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.407 |
| ISM_01065 | ISM_06475 | ISM_01065 | ISM_06475 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | COG3453 Uncharacterized protein conserved in bacteria. | 0.463 |
| ISM_01065 | ISM_07585 | ISM_01065 | ISM_07585 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Helicase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | 0.512 |
| ISM_01065 | ISM_10246 | ISM_01065 | ISM_10246 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Histone deacetylase/AcuC/AphA family protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.407 |
| ISM_01065 | ISM_10316 | ISM_01065 | ISM_10316 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.407 |
| ISM_01065 | ISM_12530 | ISM_01065 | ISM_12530 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.407 |
| ISM_01065 | prs | ISM_01065 | ISM_11760 | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Phosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.405 |
| ISM_01070 | ISM_01065 | ISM_01070 | ISM_01065 | Hypothetical protein. | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | 0.815 |
| ISM_02380 | ISM_01065 | ISM_02380 | ISM_01065 | COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | 0.407 |
| ISM_02380 | ISM_07585 | ISM_02380 | ISM_07585 | COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Helicase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | 0.868 |
| ISM_03370 | ISM_01065 | ISM_03370 | ISM_01065 | Probable acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | 0.407 |
| ISM_03370 | ISM_03375 | ISM_03370 | ISM_03375 | Probable acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.913 |
| ISM_03370 | ISM_07585 | ISM_03370 | ISM_07585 | Probable acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Helicase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | 0.868 |
| ISM_03375 | ISM_01065 | ISM_03375 | ISM_01065 | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | 0.407 |
| ISM_03375 | ISM_03370 | ISM_03375 | ISM_03370 | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Probable acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.913 |
| ISM_03375 | ISM_07585 | ISM_03375 | ISM_07585 | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Helicase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | 0.868 |
| ISM_06475 | ISM_01065 | ISM_06475 | ISM_01065 | COG3453 Uncharacterized protein conserved in bacteria. | Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | 0.463 |