Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01080 | ISM_01085 | ISM_01080 | ISM_01085 | Ribonuclease, Rne/Rng family protein; COG1530 Ribonucleases G and E. | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.908 |
| ISM_01080 | ISM_01095 | ISM_01080 | ISM_01095 | Ribonuclease, Rne/Rng family protein; COG1530 Ribonucleases G and E. | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | 0.646 |
| ISM_01080 | infA | ISM_01080 | ISM_01090 | Ribonuclease, Rne/Rng family protein; COG1530 Ribonucleases G and E. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.846 |
| ISM_01080 | yacG | ISM_01080 | ISM_01075 | Ribonuclease, Rne/Rng family protein; COG1530 Ribonucleases G and E. | Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.875 |
| ISM_01085 | ISM_01080 | ISM_01085 | ISM_01080 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Ribonuclease, Rne/Rng family protein; COG1530 Ribonucleases G and E. | 0.908 |
| ISM_01085 | ISM_01095 | ISM_01085 | ISM_01095 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | 0.650 |
| ISM_01085 | infA | ISM_01085 | ISM_01090 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.849 |
| ISM_01085 | yacG | ISM_01085 | ISM_01075 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.853 |
| ISM_01095 | ISM_01080 | ISM_01095 | ISM_01080 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Ribonuclease, Rne/Rng family protein; COG1530 Ribonucleases G and E. | 0.646 |
| ISM_01095 | ISM_01085 | ISM_01095 | ISM_01085 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.650 |
| ISM_01095 | ISM_02530 | ISM_01095 | ISM_02530 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Hypothetical protein; Belongs to the UPF0262 family. | 0.446 |
| ISM_01095 | infA | ISM_01095 | ISM_01090 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.736 |
| ISM_01095 | yacG | ISM_01095 | ISM_01075 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.629 |
| ISM_02530 | ISM_01095 | ISM_02530 | ISM_01095 | Hypothetical protein; Belongs to the UPF0262 family. | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | 0.446 |
| ISM_02530 | infA | ISM_02530 | ISM_01090 | Hypothetical protein; Belongs to the UPF0262 family. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.531 |
| ISM_02530 | yacG | ISM_02530 | ISM_01075 | Hypothetical protein; Belongs to the UPF0262 family. | Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.468 |
| ISM_04740 | yacG | ISM_04740 | ISM_01075 | YCII-related domain protein; COG2350 Uncharacterized protein conserved in bacteria. | Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.453 |
| gyrA | gyrB | ISM_16065 | ISM_05795 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.997 |
| gyrA | parE | ISM_16065 | ISM_11850 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.997 |
| gyrA | yacG | ISM_16065 | ISM_01075 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.899 |
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