| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01120 | ISM_01140 | ISM_01120 | ISM_01140 | 3-oxoacyl-(acyl carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.999 |
| ISM_01120 | ISM_16730 | ISM_01120 | ISM_16730 | 3-oxoacyl-(acyl carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | 0.461 |
| ISM_01120 | ISM_16950 | ISM_01120 | ISM_16950 | 3-oxoacyl-(acyl carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.928 |
| ISM_01120 | acpP | ISM_01120 | ISM_01130 | 3-oxoacyl-(acyl carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.985 |
| ISM_01120 | fabZ | ISM_01120 | ISM_15055 | 3-oxoacyl-(acyl carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.974 |
| ISM_01140 | ISM_01120 | ISM_01140 | ISM_01120 | COG0331 (acyl-carrier-protein) S-malonyltransferase. | 3-oxoacyl-(acyl carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.999 |
| ISM_01140 | ISM_16730 | ISM_01140 | ISM_16730 | COG0331 (acyl-carrier-protein) S-malonyltransferase. | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | 0.603 |
| ISM_01140 | acpP | ISM_01140 | ISM_01130 | COG0331 (acyl-carrier-protein) S-malonyltransferase. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.998 |
| ISM_01140 | fabZ | ISM_01140 | ISM_15055 | COG0331 (acyl-carrier-protein) S-malonyltransferase. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.956 |
| ISM_06040 | ISM_06115 | ISM_06040 | ISM_06115 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | NADH ubiquinone oxidoreductase, putative; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | 0.999 |
| ISM_06040 | ISM_14290 | ISM_06040 | ISM_14290 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; Belongs to the complex I 20 kDa subunit family. | 0.999 |
| ISM_06040 | acpP | ISM_06040 | ISM_01130 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.999 |
| ISM_06040 | nuoC | ISM_06040 | ISM_14295 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.999 |
| ISM_06040 | nuoI | ISM_06040 | ISM_14365 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.999 |
| ISM_06115 | ISM_06040 | ISM_06115 | ISM_06040 | NADH ubiquinone oxidoreductase, putative; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.999 |
| ISM_06115 | ISM_14290 | ISM_06115 | ISM_14290 | NADH ubiquinone oxidoreductase, putative; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; Belongs to the complex I 20 kDa subunit family. | 0.997 |
| ISM_06115 | acpP | ISM_06115 | ISM_01130 | NADH ubiquinone oxidoreductase, putative; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.987 |
| ISM_06115 | nuoC | ISM_06115 | ISM_14295 | NADH ubiquinone oxidoreductase, putative; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.999 |
| ISM_06115 | nuoI | ISM_06115 | ISM_14365 | NADH ubiquinone oxidoreductase, putative; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.998 |
| ISM_14290 | ISM_06040 | ISM_14290 | ISM_06040 | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; Belongs to the complex I 20 kDa subunit family. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.999 |