Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_01200COG1868 Flagellar motor switch protein. (339 aa)    
Predicted Functional Partners:
ISM_11350
COG1536 Flagellar motor switch protein.
 
 0.998
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
 0.979
ISM_05855
Possible FlgD protein; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.976
ISM_05860
Flagellar hook-length control protein.
 
  
 0.971
ISM_17360
TraF protein; COG0840 Methyl-accepting chemotaxis protein.
  
 
 0.954
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
   
   0.950
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 0.928
ISM_11520
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
  0.919
ISM_06625
Response regulator; COG0784 FOG: CheY-like receiver.
 
 
  0.917
ISM_01565
Response regulator receiver protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
  
 0.913
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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