STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_01300COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit. (127 aa)    
Predicted Functional Partners:
ISM_01290
COG4765 Uncharacterized protein conserved in bacteria.
 
     0.943
ISM_01295
Hypothetical protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.
     
 0.854
ISM_13080
NADH-ubiquinone oxidoreductase family protein.
  
    0.783
clpX
ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
    0.661
ISM_05330
Hypothetical protein; COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase.
  
     0.642
atpE
FoF1 ATP synthase, subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
     0.612
ISM_06785
Transporter, Tim44 family protein; COG4395 Uncharacterized protein conserved in bacteria.
  
     0.574
ISM_12425
COG3814 Uncharacterized protein conserved in bacteria.
 
   
 0.561
ISM_06570
COG0500 SAM-dependent methyltransferases.
  
     0.538
ISM_04840
COG3474 Cytochrome c2.
  
     0.526
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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