Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_01365COG5319 Uncharacterized protein conserved in bacteria. (143 aa)    
Predicted Functional Partners:
ISM_01370
Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.759
ISM_01360
Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
       0.648
ISM_01375
Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family.
       0.563
ISM_07160
COG3741 N-formylglutamate amidohydrolase.
 
     0.536
ISM_00380
Cobalt chelatase, pCobT subunit; COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
     0.534
ISM_00370
Cobalt chelatase, CobS subunit; COG5271 AAA ATPase containing von Willebrand factor type A (vWA) domain.
  
     0.519
ISM_14450
COG3807 Uncharacterized protein conserved in bacteria.
  
     0.436
ISM_07270
COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.
  
     0.419
ISM_01385
Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.
 
     0.402
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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